Christopher E Brightling Selected Research

COVID-19

1/2024	Post-acute COVID-19 neuropsychiatric symptoms are not associated with ongoing nervous system injury.
1/2024	Plasma steroid concentrations reflect acute disease severity and normalise during recovery in people hospitalised with COVID-19.
10/2023	Acute blood biomarker profiles predict cognitive deficits 6 and 12 months after COVID-19 hospitalization.
3/2023	Nebulised interferon-β1a (SNG001) in hospitalised COVID-19: SPRINTER phase III study.
1/2022	Association of gut-related metabolites with respiratory symptoms in COVID-19: A proof-of-concept study.
11/2021	Alterations in T and B cell function persist in convalescent COVID-19 patients.
11/2021	Symptom Persistence Despite Improvement in Cardiopulmonary Health - Insights from longitudinal CMR, CPET and lung function testing post-COVID-19.
7/2021	Diagnosis of COVID-19 by exhaled breath analysis using gas chromatography-mass spectrometry.

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Christopher E Brightling Research Topics

Disease

106	Asthma (Bronchial Asthma) 04/2024 - 04/2002
50	Inflammation (Inflammations) 02/2024 - 12/2002
47	Chronic Obstructive Pulmonary Disease (COPD) 11/2023 - 10/2003
10	Eosinophilia 02/2024 - 01/2005
9	Airway Remodeling 04/2024 - 06/2012
9	Bronchitis 07/2019 - 05/2002
8	Infections 01/2024 - 06/2011
8	COVID-19 01/2024 - 07/2021
8	Cough 01/2020 - 01/2003
7	Respiratory Hypersensitivity 01/2023 - 12/2002
5	Bacterial Infections (Bacterial Infection) 07/2021 - 06/2011
5	Chronic Cough 01/2020 - 01/2004
4	Symptom Flare Up 01/2022 - 01/2022
3	Acute Disease 01/2024 - 01/2019
3	Airway Obstruction (Choking) 10/2023 - 06/2012
3	Dyspnea (Shortness of Breath) 01/2023 - 01/2019
3	Wounds and Injuries (Trauma) 01/2021 - 06/2012
2	Emphysema 01/2021 - 01/2020
2	Rhinosinusitis 01/2021 - 07/2019
2	Pneumonia (Pneumonitis) 09/2015 - 06/2011
1	Nervous System Trauma 01/2024
1	Thyroid Diseases (Thyroid Disease) 10/2023

Drug/Important Bio-Agent (IBA)

41	Biomarkers (Surrogate Marker)IBA 04/2024 - 01/2005
40	Adrenal Cortex Hormones (Corticosteroids)IBA 10/2023 - 01/2003
15	CytokinesIBA 04/2024 - 12/2002
11	Bronchodilator Agents (Bronchodilators)IBA 04/2024 - 02/2006
9	tezepelumabIBA 04/2024 - 01/2021
9	Monoclonal AntibodiesIBA 01/2022 - 01/2018
9	Interleukin-13IBA 01/2021 - 11/2004
8	16S Ribosomal RNAIBA 01/2021 - 04/2016
7	Interleukin-33IBA 04/2024 - 09/2015
7	SteroidsIBA 01/2024 - 01/2012
6	InterleukinsIBA 04/2024 - 09/2015
6	Proteins (Proteins, Gene)FDA Link 11/2023 - 07/2010
6	mepolizumabIBA 10/2021 - 03/2009
5	Nitric Oxide (Nitrogen Monoxide)FDA Link 04/2024 - 01/2005
5	AllergensIBA 01/2023 - 06/2012
5	Immunoglobulin E (IgE)IBA 01/2020 - 12/2010
4	tralokinumabIBA 10/2022 - 09/2015
4	Formoterol Fumarate (Oxis)FDA Link 01/2022 - 01/2022
4	3- (2- (4- azidobenzamidino)ethyl)- 5- hydroxyindole (SABA)IBA 01/2022 - 01/2022
4	Muscarinic AntagonistsIBA 01/2022 - 01/2022
4	Azithromycin (Zithromax)FDA LinkGeneric 01/2022 - 01/2022
4	Anti-Bacterial Agents (Antibiotics)IBA 10/2021 - 06/2011
4	C-Reactive ProteinIBA 10/2021 - 06/2011
4	benralizumabIBA 01/2021 - 11/2014
4	ChemokinesIBA 01/2020 - 05/2005
3	Thymic Stromal LymphopoietinIBA 05/2024 - 01/2021
3	Interleukin-17 (Interleukin 17)IBA 04/2024 - 11/2010
3	Prostaglandin D2IBA 02/2024 - 01/2004
3	dupilumabIBA 02/2024 - 03/2023
3	GlucocorticoidsIBA 01/2024 - 01/2015
3	RNA (Ribonucleic Acid)IBA 10/2023 - 12/2020
3	Volatile Organic CompoundsIBA 11/2022 - 01/2019
3	Interleukin-6 (Interleukin 6)IBA 03/2022 - 07/2021
3	Immunoglobulin G (IgG)IBA 01/2022 - 12/2010
3	SmokeIBA 01/2022 - 08/2015
3	prostaglandin D2 receptorIBA 01/2021 - 01/2016
3	fevipiprantIBA 01/2021 - 01/2016
3	LigandsIBA 04/2016 - 05/2005
3	Prednisolone (Predate)FDA LinkGeneric 01/2016 - 07/2010
3	Chemokine ReceptorsIBA 12/2006 - 12/2002
2	Histamine (Histamine Dihydrochloride)FDA Link 02/2024 - 01/2004
2	AntioxidantsIBA 01/2022 - 01/2018
2	OvalbuminIBA 01/2022 - 01/2016
2	astegolimabIBA 01/2022 - 01/2021
2	Toll-Like Receptors (Toll-Like Receptor)IBA 11/2021 - 10/2006
2	Mannitol (Osmitrol)FDA LinkGeneric 11/2021 - 11/2008
2	Interleukin-6 Receptors (Interleukin 6 Receptor)IBA 10/2021 - 01/2018
2	Interleukin-5 (Interleukin 5)IBA 10/2021 - 01/2021
2	AlarminsIBA 01/2021 - 09/2015
2	CalciumIBA 01/2021 - 12/2020
2	Butyrates (Butyrate)IBA 11/2020 - 01/2020
2	GoldIBA 01/2020 - 01/2016
2	Protein Isoforms (Isoforms)IBA 01/2020 - 08/2015
2	Messenger RNA (mRNA)IBA 01/2020 - 01/2019
2	Interleukin-5 Receptors (Interleukin 5 Receptor)IBA 12/2019 - 01/2019
2	PeriostinIBA 01/2018 - 09/2015
2	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 01/2018 - 07/2012
2	Urokinase Plasminogen Activator ReceptorsIBA 08/2015 - 06/2012
2	Histones (Histone)IBA 05/2015 - 07/2012
2	Phenobarbital (Luminal)FDA Link 02/2013 - 06/2012
2	GTP-Binding Proteins (G-Protein)IBA 06/2012 - 01/2012
2	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 07/2010 - 02/2006
2	Methacholine Chloride (Methacholine)FDA Link 02/2006 - 04/2002
1	LeukotrienesIBA 02/2024
1	Cysteine (L-Cysteine)FDA Link 02/2024
1	Hormones (Hormone)IBA 01/2024
1	Glial Fibrillary Acidic ProteinIBA 01/2024
1	Testosterone (Sustanon)FDA Link 01/2024
1	Gonadal Steroid Hormones (Sex Hormones)IBA 01/2024
1	tau Proteins (tau Protein)IBA 01/2024
1	Hydrocortisone (Cortisol)FDA LinkGeneric 01/2024
1	Thyrotropin (Thyroid-Stimulating Hormone)FDA Link 10/2023
1	VaccinesIBA 03/2023

Therapy/Procedure

45	Therapeutics 04/2024 - 01/2003
9	Biological Therapy 01/2023 - 01/2020
4	Bronchial Thermoplasty 11/2019 - 01/2014
3	Precision Medicine 01/2020 - 11/2016
1	Artificial Respiration (Mechanical Ventilation) 03/2023